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Article

FGF receptor mutations: dimerization syndromes, cell growth suppression, and animal models.

IUBMB life - 1 Mar 2000

Kannan K, Givol D

Abstract excerpt

This review describes recent progress in the field of fibroblast growth factor receptors (FGFRs) with an emphasis on the role of FGFR mutants in skeletal malformations. This family of four receptors contains the most frequent germline mutations in humans. More than 75 mutations have been recorded, which account for more than seven skeletal syndromes. The common cause for all the mutant phenotypes is...

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Source

Identifiers

PMID: 10868910
DOI: 10.1080/713803609

Genes

FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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