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Article

The FGF21 Receptor Signaling Complex: Klothoβ, FGFR1c, and Other Regulatory Interactions.

Vitamins and hormones - 1 Jan 2016

Kilkenny D M, Rocheleau J V

Abstract excerpt

Scientific evidence is quickly growing that establishes FGF21 as a cytokine that signals both locally and systemically to induce metabolic effects. The focus of this chapter is the receptor/co-receptor signaling complex formed by endocrine FGF21. We provide an introduction to the major components of the complex including the Klotho family of co-receptors, fibroblast growth factor receptors (FGFRs), and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27125737
DOI: 10.1016/bs.vh.2016.02.008

Genes

FGF21
KLB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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