Article
Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction.
Trends in cell biology - 1 Apr 2015
Carter Edward P, Fearon Abbie E, Grose Richard P
Abstract excerpt
Since its discovery 40 years ago, fibroblast growth factor (FGF) receptor (FGFR) signalling has been found to regulate fundamental cellular behaviours in a wide range of cell types. FGFRs regulate development, homeostasis, and repair and are implicated in many disorders and diseases; and indeed, there is extensive potential for severe consequences, be they developmental, homeostatic, or oncogenic, should FGF-FGFR...
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