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Article

Association of multiple drug resistance-1 gene polymorphism with multiple drug resistance in breast cancer patients from an ethnic Saudi Arabian population.

Cancer epidemiology - 1 Oct 2013

Alsaif Abdulaziz A, Hasan Tarique N, Shafi Gowhar, Syed Naveed A, Alsaif Mohammed A, Al-Assaf Abdullah H, Alshatwi Ali A

Abstract excerpt

Chemotherapy has been used widely to treat cancer, both as a systemic therapy and as a local treatment. Unfortunately, many types of cancer are still refractory to chemotherapy. The mechanisms of anticancer drug resistance have been extensively explored but have not been fully characterized. This study analyzed the occurrences of polymorphism (SNP) in the MDR1 gene in breast cancer patients and determined a...

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Identifiers

PMID: 23725642
DOI: 10.1016/j.canep.2013.04.011

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