Article
In vivo regulation of the chicken cardiac troponin T gene promoter in zebrafish embryos.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Aug 2003
Tidyman William E, Sehnert Amy J, Huq Anja, Agard Jennifer, Deegan Fiona, Stainier Didier Y R, Ordahl Charles P
Abstract excerpt
The chicken cardiac troponin T (cTnT) gene is representative of numerous cardiac and skeletal muscle-specific genes that contain muscle-CAT (MCAT) elements within their promoters. We examined the regulation of the chicken cTnT gene in vivo in zebrafish embryos, and in vitro in cardiomyocyte, myoblast, and fibroblast cultures. Defined regions of the cTnT promoter were linked to the green fluorescent protein (GFP)...
Topics
- Animals
- Animals, Genetically Modified
- Base Sequence
- Binding Sites
- Cells, Cultured
- Chick Embryo
- Chickens
- Enhancer Elements, Genetic
- Evolution, Molecular
- Gene Components
