Article
Muscle-enriched TEF-1 isoforms bind M-CAT elements from muscle-specific promoters and differentially activate transcription.
The Journal of biological chemistry - 4 Feb 1994
Stewart A F, Larkin S B, Farrance I K, Mar J H, Hall D E, Ordahl C P
Abstract excerpt
M-CAT elements mediate cardiac- and embryonic skeletal muscle-specific expression of the cardiac troponin T gene and a number of other cardiac-specific genes. M-CAT binding factor was shown to be related to cloned human TEF-1, a transcriptional regulator of the SV40 viral enhancer. Here we descri...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Chick Embryo
- Chickens
- Cloning, Molecular
- DNA Primers
- DNA-Binding Proteins
- Exons
- Gene Expression
- Gene Expression Regulation
- Genetic Variation
- Humans
- Molecular Sequence Data
- Muscle Proteins
- Muscles
- Nuclear Proteins