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Article

Mef2c is an essential regulatory element required for unique expression of the cardiac-specific CARK gene.

Journal of cellular and molecular medicine - 1 Jan 2000

Wang Hu, Chen Chen, Song Xiaodong, Chen Jingzhou, Zhen Yisong, Sun Kai, Hui Rutai

Abstract excerpt

The cardiac ankyrin repeat kinase (CARK) gene, also named TNNI3K for its interaction with cardiac troponin I, is both a unique expression and heart-enriched gene. To understand the mechanisms of CARK gene expression and regulation, we first cloned the full-length mRNA sequence and mapped the transcription start site of the mouse CARK gene and characterized its promoter regions. Two transcriptional isoforms of the...

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Identifiers

PMID: 18021318
DOI: 10.1111/j.1582-4934.2007.00155.x
PMCID: PMC3823491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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