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Article

Silencing near tRNA genes is nucleosome-mediated and distinct from boundary element function.

Gene - 15 Aug 2013

Good Paul D, Kendall Ann, Ignatz-Hoover James, Miller Erin L, Pai Dave A, Rivera Sara R, Carrick Brian, Engelke David R

Abstract excerpt

Transfer RNA (tRNA) genes and other RNA polymerase III transcription units are dispersed in high copy throughout nuclear genomes, and can antagonize RNA polymerase II transcription in their immediate chromosomal locus. Previous work in Saccharomyces cerevisiae found that this local silencing required subnuclear clustering of the tRNA genes near the nucleolus. Here we show that the silencing also requires...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23707796
DOI: 10.1016/j.gene.2013.05.016
PMCID: PMC3745993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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