RNA polymerase III and RNA polymerase II promoter complexes are heterochromatin barriers in Saccharomyces cerevisiae.

doi:10.1093/emboj/20.3.520

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Article

RNA polymerase III and RNA polymerase II promoter complexes are heterochromatin barriers in Saccharomyces cerevisiae.

The EMBO journal - 1 Feb 2001

Donze D, Kamakaka R T

Abstract excerpt

The chromosomes of eukaryotes are organized into structurally and functionally discrete domains. Several DNA elements have been identified that act to separate these chromatin domains. We report a detailed characterization of one of these elements, identifying it as a unique tRNA gene possessing the ability to block the spread of silent chromatin in Saccharomyces cerevisiae efficiently. Transcriptional potential...

Topics

Acetyltransferases
Gene Expression
Gene Silencing
Genes, Fungal
Heterochromatin
Models, Biological
Mutation
Promoter Regions, Genetic
RNA Polymerase II
RNA Polymerase III
RNA, Transfer, Thr
Saccharomyces cerevisiae
Transcription Factors

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Identifiers

PMID: 11157758
DOI: 10.1093/emboj/20.3.520
PMCID: PMC133458

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