Article
Coordination of tRNA transcription with export at nuclear pore complexes in budding yeast.
Genes & development - 1 May 2014
Chen Miao, Gartenberg Marc R
Abstract excerpt
tRNAs are encoded by RNA polymerase III-transcribed genes that reside at seemingly random intervals along the chromosomes of budding yeast. Existing evidence suggests that the genes congregate together at the nucleolus and/or centromeres. In this study, we re-examined spatial and temporal aspects of tRNA gene (tDNA) expression. We show that tDNA transcription fluctuates during cell cycle progression. In M phase,...
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