Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of the vaccinia virus gene encoding an 18-kilodalton subunit of RNA polymerase and demonstration of a 5' poly(A) leader on its early transcript.

Journal of virology - 1 Jun 1990

Ahn B Y, Jones E V, Moss B

Abstract excerpt

The DNA-dependent RNA polymerase of vaccinia virus contains 8 to 10 virus-encoded polypeptides. We have mapped the gene encoding an 18-kilodalton RNA polymerase subunit to D7R, the seventh open reading frame of the HindIII D genomic subfragment. Localization of this gene was achieved by using antibody to the purified RNA polymerase for immunoprecipitation of the in vitro translation products of in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Molecular Sequence Data
Share to Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Promoter Regions, Genetic

Share to Restriction Mapping

Share to RNA, Viral

Share to Temperature

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 2335825
DOI: 10.1128/JVI.64.6.3019-3024.1990
PMCID: PMC249486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of the vaccinia virus gene encoding an 18-kilodalton subunit of RNA polymerase and demonstration of a 5' poly(A) leader on its early transcript.PMID 2335825Read ↗

The vaccinia virus A18R protein plays a role in viral transcription during both the early and the late phases of infection.Semantic proximity Read ↗

Vaccinia virus A19 protein participates in the transformation of spherical immature particles to barrel-shaped infectious virions.Semantic proximity Read ↗

The vaccinia virus A18R DNA helicase is a postreplicative negative transcription elongation factor.Semantic proximity Read ↗

Temperature-sensitive mutations in the gene encoding the small subunit of the vaccinia virus early transcription factor impair promoter binding, transcription activation, and packaging of multiple virion components.Semantic proximity Read ↗

The A2L intermediate gene product is required for in vitro transcription from a vaccinia virus late promoter.Semantic proximity Read ↗

Vaccinia virus directs the synthesis of early mRNAs containing 5' poly(A) sequences.Semantic proximity Read ↗

Structure and expression of the vaccinia virus gene which prevents virus-induced breakdown of RNA.Semantic proximity Read ↗

Repression of the A8L gene, encoding the early transcription factor 82-kilodalton subunit, inhibits morphogenesis of vaccinia virions.Semantic proximity Read ↗

Vaccinia virus gene A18R DNA helicase is a transcript release factor.Semantic proximity Read ↗

Vaccinia virus WR gene A5L is required for morphogenesis of mature virions.Semantic proximity Read ↗

Reduced Polyomavirus DNA replication as a consequence of a late-region deletion that results in early mRNA instability.Semantic proximity Read ↗

Temperature-sensitive mutants in the vaccinia virus A18R gene increase double-stranded RNA synthesis as a result of aberrant viral transcription.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.