Article
Stalled RNAP-II molecules bound to non-coding rDNA spacers are required for normal nucleolus architecture.
Yeast (Chichester, England) - 1 Jul 2013
Freire-Picos M A, Landeira-Ameijeiras V, Mayán María D
Abstract excerpt
The correct distribution of nuclear domains is critical for the maintenance of normal cellular processes such as transcription and replication, which are regulated depending on their location and surroundings. The most well-characterized nuclear domain, the nucleolus, is essential for cell survival and metabolism. Alterations in nucleolar structure affect nuclear dynamics; however, how the nucleolus and the rest...
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