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Nucleolar Adaptation in Human Cancer

1 Jan 2005

Abstract excerpt

While the nucleolus was first observed over two hundred years ago, its role in human cancers is only now being appreciated. Long thought to be a static, ribosome-producing, subnuclear organelle, recent investigations have shown a more dynamic and adaptable side of the nucleolus. Containing not only proteins for the production of ribosomes but also newfound nucleolar oncogenes and tumor suppressors, mechanistic...

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PMID: 16305988
DOI: 10.1080/07357900500283085

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