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Treacle Sticks the Nucleolar Responses to DNA Damage Together

12 May 2022

Abstract excerpt

The importance of chromatin environment for DNA repair has gained increasing recognition in recent years. The nucleolus is the largest sub-compartment within the nucleus: it has distinct biophysical properties, selective protein retention, and houses the specialized ribosomal RNA genes (collectively referred to as rDNA) with a unique chromatin composition. These genes have high transcriptional activity and a...

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PMID: 35646927
DOI: 10.3389/fcell.2022.892006

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