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Article

Analysis of PITX3 gene in patients with multisystem atrophy, progressive supranuclear palsy and corticobasal degeneration.

Annals of clinical and laboratory science - 1 Jan 2013

Jamrozik Zygmunt, Berdynski Mariusz, Zekanowski Cezary, Baranczyk-Kuzma Anna, Sławek Jarosław, Kuzma-Kozakiewicz Magdalena, Maruszak Aleksandra, Kwiecinski Hubert

Abstract excerpt

Interactions of transcriptions factors Nurr1, Pitx3, and EN1 are involved in the maturation and survival of adult midbrain dopaminergic neurons during a lifetime. The aim of the study was to evaluate the presence of mutations and single nucleotide polymorphisms in PITX3 gene in clinically diagnosed multisystem atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD). In the group...

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PMID: 23694789

Genes

PITX3

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