Transcription factor PITX3 gene in Parkinson's disease.

doi:10.1016/j.neurobiolaging.2009.03.015

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Article

Transcription factor PITX3 gene in Parkinson's disease.

Neurobiology of aging - 1 Apr 2011

Le Weidong, Nguyen Deanne, Lin Xiyao Wendy, Rawal Pawan, Huang Maosheng, Ding Yujian, Xie Wenjie, Deng Hao, Jankovic Joseph

Abstract excerpt

PITX3 is a transcription factor important for the differentiation and survival of midbrain dopaminergic neurons during the development. Recent reports suggest that single nucleotide polymorphisms (SNP) in the gene may be associated with Parkinson's disease (PD). To verify their findings and to determine the nature of the association in a subset of our PD patients we have analyzed two PITX3 SNPs (rs2281983 and...

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Identifiers

PMID: 19394114
DOI: 10.1016/j.neurobiolaging.2009.03.015

Genes

PITX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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