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Article

Genetic analysis of PITX3 variants in patients with essential tremor.

Acta neurologica Scandinavica - 1 Mar 2017

Chen H, Song Z, Yuan L, Xiong W, Yang Z, Gong L, Deng H

Abstract excerpt

BACKGROUND: A clinical overlap between essential tremor (ET) and Parkinson's disease (PD) has prompted investigation whether these disorders share common genetic factors. The paired-like homeodomain transcription factor 3 gene (PITX3) has been shown to play an important role for the differentiation and survival of midbrain dopaminergic neurons in the substantia nigra pars compacta. The preferential degeneration...

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Source

Identifiers

PMID: 27145793
DOI: 10.1111/ane.12608

Genes

PITX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic analysis of PITX3 variants in patients with essential tremor.PMID 27145793Read ↗

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