Article
Systematic genetic analysis of the PITX3 gene in patients with Parkinson disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Aug 2011
Guo Yi, Le Wei-Dong, Jankovic Joseph, Yang Hua-Rong, Xu Hong-Bo, Xie Wen-Jie, Song Zhi, Deng Hao
Abstract excerpt
BACKGROUND: Paired-like homodomain transcription factor 3 has been found to be important for the differentiation and survival of midbrain dopaminergic neurons. METHODS: To determine whether genetic variation in the coding region of the paired-like homodomain transcription factor 3 gene plays a role in Parkinson's disease, genetic analysis was performed in 112 patients with Parkinson's disease. RESULTS: We did not...
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