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Article

A novel synonymous SNP in PITX3 is associated with Parkinson's disease in Chinese population.

Swiss medical weekly - 1 Jan 2012

Gui Yaxing, Zhao Yijia, Liu Hai, Fu Jiang, Xu Zhongping, Hu Xingyue

Abstract excerpt

BACKGROUND AND PURPOSE: Paired-like homeodomain transcription factor 3 (PITX3) is an important transcription factor for differentiation and survival of dopaminergic neurons. Recent reports have shown a strong association of polymorphisms in the PITX3 gene with Parkinson's disease (PD). Our study was designed to verify whether three previous PITX3 SNPs (rs2281983, rs4919621 and rs3758549) were associated with PD...

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Source

Identifiers

PMID: 22411443
DOI: 10.4414/smw.2012.13521

Genes

PITX3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel synonymous SNP in PITX3 is associated with Parkinson's disease in Chinese population.PMID 22411443Read ↗

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Association between PITX3 promoter polymorphism and risk of Parkinson's disease: the impact of ethnicity and onset age.Semantic proximity Read ↗

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