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Article

Association between MDM2 SNP309 T>G and risk of gastric cancer: a meta-analysis.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013

Tian Xin, Tian Ye, Ma Ping, Sui Cheng-Guang, Meng Fan-Dong, Li Yan, Fu Li-Ye, Jiang Tao, Wang Yang, Ji Fu-Jian, Fang Xue-Dong, Jiang You-Hong

Abstract excerpt

BACKGROUND: As a negative regulator of P53, MDM2 plays an important role in carcinogenesis; a polymorphism in its promoter region. SNP309 T>G, is known to increase the expression of MDM2, thus being considered related to higher susceptibility to neoplasia. However, no agreement has been achieved regarding its effects on gastric cancer. METHODS: The present systematic meta-analysis was performed based on...

Topics

Case-Control Studies
Genetic Predisposition to Disease
Humans
Polymorphism, Single Nucleotide
Prognosis
Proto-Oncogene Proteins c-mdm2
Risk Factors
Stomach Neoplasms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23679294
DOI: 10.7314/apjcp.2013.14.3.1925

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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