Article
No association of MDM2 T309G polymorphism with susceptibility to Korean gastric cancer patients.
Neoplasma - 1 Jan 2008
Cho Y G, Choi B J, Song J H, Kim C J, Cao Z, Nam S W, Lee J Y, Park W S
Abstract excerpt
Mouse double minute 2 (Mdm2) acts as a negative regulator of p53 by binding to the amino-terminus of p53. The common T309G polymorphism of Mdm2 has been the most frequently investigated, which can influence in cancer susceptibility and disease outcome. The specific aim of this study is to investigate whether the T309G polymorphism of Mdm2 was associated with individual susceptibility to gastric cancer in Korea....
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