Article
MDM2 309 T/G polymorphism is associated with colorectal cancer risk especially in Asians: a meta-analysis.
Medical oncology (Northwood, London, England) - 1 Dec 2011
Fang Fang, Yu Xiao-Jia, Yu Lu, Yao Lei
Abstract excerpt
The murine double minute 2 (MDM2) gene encodes an important regulator which mainly functions as an E3 ligase. The role of the MDM2 protein in the P53 pathway has been especially well-studied. In this study, our aim was to explore the relationship between MDM2 gene 309 T/G polymorphism and colorectal cancer risk. Performing both the overall meta-analysis and the subgroup meta-analysis based on ethnicity and source...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
