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Helicobacter pylori infection and MDM2 SNP309 association with gastric cancer susceptibility.

Genetic testing and molecular biomarkers - 1 Nov 2013

Moradi Mohammad Taher, Salehi Zivar, Asl Saba Fakhrieh, Aminian Keyvan, Hashtchin Anna Rafiei

Abstract excerpt

AIMS: MDM2 is a negative regulator of p53, and has also been implicated in carcinogenesis. The aim of this study was to define the causal association of Helicobacter pylori infection and the MDM2 SNP309 among northern Iranian patients with gastric cancer (GC). Two hundred and eight patients with GC and 200 cancer-free controls were genotyped for MDM2 SNP309 using the polymerase chain reaction-restriction fragment...

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Identifiers

PMID: 24010568
DOI: 10.1089/gtmb.2013.0173

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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