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Article

JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy.

Kidney international - 1 Dec 2013

Divers Jasmin, Núñez Marina, High Kevin P, Murea Mariana, Rocco Michael V, Ma Lijun, Bowden Donald W, Hicks Pamela J, Spainhour Mitzie, Ornelles David A, Kleiboeker Steven B, Duncan Kara, Langefeld Carl D, Turner Jolyn, Freedman Barry I

Abstract excerpt

Individuals with HIV infection and two apolipoprotein L1 gene (APOL1) risk variants frequently develop nephropathy. Here we tested whether non-HIV viral infections influence nephropathy risk via interactions with APOL1 by assessing APOL1 genotypes and presence of urine JC and BK polyoma virus and plasma HHV6 and CMV by quantitative polymerase chain reaction. We analyzed 300 samples from unrelated and related...

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Identifiers

PMID: 23677244
DOI: 10.1038/ki.2013.173
PMCID: PMC3844025

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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