Article
Apolipoprotein L1 gene variants and kidney disease in patients with HIV: a systematic review and meta-analysis.
Journal of nephrology - 1 May 2023
Waziri Bala, Raji Yakubu Egigogo, Ekrikpo Udeme E, Naicker Saraladevi
Abstract excerpt
BACKGROUND: The risk of various types of kidney disease is significantly increased in the presence of APOL1 high-risk genotype (carriage of two risk alleles), particularly HIV-associated nephropathy (HIVAN). However, there are discrepancies in the existing evidence about the level of association between APOL1 high-risk genotype and the risk of kidney diseases in people living with HIV (PLWHIV). METHODS: This...
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