Article
The evolving science of apolipoprotein-L1 and kidney disease.
Current opinion in nephrology and hypertension - 1 May 2016
Chen Teresa K, Estrella Michelle M, Parekh Rulan S
Abstract excerpt
PURPOSE OF REVIEW: There are evolving epidemiological and biological data to support an association between the gene encoding apolipoprotein-L1 (APOL1) and progressive chronic kidney disease (CKD) among African-Americans. RECENT FINDINGS: Individuals with two APOL1 risk alleles are at greater risk of incident albuminuria, CKD, and progression to end-stage renal disease despite optimal blood pressure management...
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