Article
JC polyoma viruria associates with protection from chronic kidney disease independently from apolipoprotein L1 genotype in African Americans.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Nov 2018
Freedman Barry I, Kistler Amy L, Skewes-Cox Peter, Ganem Don, Spainhour Mitzie, Turner Jolyn, Divers Jasmin, Langefeld Carl D, Murea Mariana, Hicks Pamela J, Hemal Ashok K, Snipes James A, Zhao Lihong, Abend Johanna R, Lyles Douglas S, Ma Lijun, Skorecki Karl L
Abstract excerpt
Background: Viral infections can trigger chronic kidney disease (CKD) and the urine virome may inform risk. The Natural History of APOL1-Associated Nephropathy Study (NHAANS) reported that urine JC polyomavirus (JCPyV) associated with a lower risk of APOL1-associated nephropathy in African Americans. Herein, association was assessed between urine JCPyV with CKD in African Americans independent from the APOL1...
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