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Article

Polymorphisms and haplotypes in TLR9 and MYD88 are associated with the development of Hodgkin's lymphoma: a candidate-gene association study.

Journal of human genetics - 1 Nov 2009

Mollaki Vassiliki, Georgiadis Thomas, Tassidou Anna, Ioannou Maria, Daniil Zoe, Koutsokera Aggeliki, Papathanassiou Aphrodite A, Zintzaras Elias, Vassilopoulos George

Abstract excerpt

Toll-like receptors (TLRs) and myeloid differentiation primary response protein 88 (MYD88) gene polymorphisms may be involved in the pathogenesis of Hodgkin's lymphoma (HL) through altered immunoregulatory and inflammatory responses. A candidate-gene association study was conducted to investigate the association between TLR9 -1237T>C, TLR9 2848A>G, MYD88 -938C>A and MYD88 1944C>G gene polymorphisms and the risk...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19745833
DOI: 10.1038/jhg.2009.90

Genes

MYD88
TLR9

Provenance

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