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Article

Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants.

Circulation. Cardiovascular genetics - 1 Jun 2013

Leonard Dag, Svenungsson Elisabet, Sandling Johanna K, Berggren Olof, Jönsen Andreas, Bengtsson Christine, Wang Chuan, Jensen-Urstad Kerstin, Granstam Sven-Olof, Bengtsson Anders A, Gustafsson Johanna T, Gunnarsson Iva, Rantapää-Dahlqvist Solbritt, Nordmark Gunnel, Eloranta Maija-Leena, Syvänen Ann-Christine, Rönnblom Lars

Abstract excerpt

BACKGROUND: Patients with systemic lupus erythematosus have increased morbidity and mortality in coronary heart disease (CHD). We asked whether there was a genetic influence on CHD in systemic lupus erythematosus. METHODS AND RESULTS: The association between single-nucleotide polymorphisms (SNPs) and CHD in 2 populations of patients with systemic lupus erythematosus was assessed. Patients were genotyped on a...

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PMID: 23661672
DOI: 10.1161/CIRCGENETICS.113.000044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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