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Article

Genetic analysis of leukocyte type-I interferon production and risk of coronary artery disease.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2015

Nelson Christopher P, Schunkert Heribert, Samani Nilesh J, Erridge Clett

Abstract excerpt

OBJECTIVE: Patients with systemic lupus erythematosus are genetically predisposed to enhanced production of the type-I interferon IFN-α and are also at elevated risk of developing atherosclerosis compared with healthy subjects. We aimed to test whether genetic predisposition to increased type-I IFN production affects risk of coronary artery disease. APPROACH AND RESULTS: Using a list of 11 single nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25882064
DOI: 10.1161/ATVBAHA.114.304925

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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