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Association between Systemic Lupus Erythematosus and Coronary Heart Disease: a retrospective case-control analysis and Mendelian Randomization Study

2021-11-24

Abstract excerpt

<h4>Objectives</h4> To appraise the causal effect of systemic lupus erythematosus (SLE) for risk of Coronary heart disease (CHD). <h4>Methods</h4> We selected single nucleotide polymorphisms (SNPs) associated with SLE as instrumental variables (IVs) from three independent genome-wide association studies (GWAS), the three largest to date for SLE of European ancestry. Then we conducted two-sample Mendelian randomiza...

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Literature Corpus work
96357efb-f62e-5267-884f-32382e78d204
DOI
10.1101/2021.11.23.21266652
Open publication

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Association between Systemic Lupus Erythematosus and Coronary Heart Disease: a retrospective case-control analysis and Mendelian Randomization StudyDOI 10.1101/2021.11.23.21266652
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