Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis.

doi:10.1136/annrheumdis-2017-212614

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Article

Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis.

Annals of the rheumatic diseases - 1 Jul 2018

Leonard Dag, Svenungsson Elisabet, Dahlqvist Johanna, Alexsson Andrei, Ärlestig Lisbeth, Taylor Kimberly E, Sandling Johanna K, Bengtsson Christine, Frodlund Martina, Jönsen Andreas, Eketjäll Susanna, Jensen-Urstad Kerstin, Gunnarsson Iva, Sjöwall Christopher, Bengtsson Anders A, Eloranta Maija-Leena, Syvänen Ann-Christine, Rantapää-Dahlqvist Solbritt, Criswell Lindsey A, Rönnblom Lars

Abstract excerpt

OBJECTIVES: Patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) have increased risk of cardiovascular disease (CVD). We investigated whether single nucleotide polymorphisms (SNPs) at autoimmunity risk loci were associated with CVD in SLE and RA. METHODS: Patients with SLE (n=1045) were genotyped using the 200K Immunochip SNP array (Illumina). The allele frequency was compared between...

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PMID: 29514802
DOI: 10.1136/annrheumdis-2017-212614
PMCID: PMC6029634

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SRP54

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