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Article

EpiDOCK: a molecular docking-based tool for MHC class II binding prediction.

Protein engineering, design & selection : PEDS - 1 Oct 2013

Atanasova Mariyana, Patronov Atanas, Dimitrov Ivan, Flower Darren R, Doytchinova Irini

Abstract excerpt

Cellular peptide vaccines contain T-cell epitopes. The main prerequisite for a peptide to act as a T-cell epitope is that it binds to a major histocompatibility complex (MHC) protein. Peptide MHC binder identification is an extremely costly experimental challenge since human MHCs, named human leukocyte antigen, are highly polymorphic and polygenic. Here we present EpiDOCK, the first structure-based server for MHC...

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Identifiers

PMID: 23661105
DOI: 10.1093/protein/gzt018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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