Article
The (TTTA)n polymorphism in intron 4 of CYP19 and the polycystic ovary syndrome risk in a Chinese population.
Molecular biology reports - 1 Aug 2013
Xu P, Zhang X L, Xie G B, Zhang C W, Shen S M, Zhang X X, Cao Y X, Wang W J, Che Y N, Xia Y J, Wu X K, Yi L, Gao Q, Wang Y
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a heterogeneous disease with a strong genetic origin, but the specific determinants are still unknown. The aim of this study was to investigate the association between the (TTTA) n polymorphism in intron 4 of CYP19 and the PCOS risk in a Chinese population. We performed a case-control study which involved 222 PCOS patients and 281 controls. The fluorescent-labeled target DNA...
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