Article
CYP11A1 microsatellite (tttta)n polymorphism in PCOS women from South India.
Journal of assisted reproduction and genetics - 1 Jul 2014
Reddy K Ranjith, Deepika M L N, Supriya K, Latha K Prasanna, Rao S S Lakshmana, Rani V Usha, Jahan P
Abstract excerpt
BACKGROUND: Polycystic ovary syndrome (PCOS) is a condition with central feature of hyperandrogensism that affects 5-12 % of women worldwide. P450sec the cholesterol side chain cleavage enzyme encoded by CYP11A1 gene is instrumental in the synthesis of sex hormones. A promoter pentanucleotide repeat (tttta)(n) polymorphism of this gene is reported to be associated with several hormone related diseases including...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
