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Polymorphisms of pentanucleotide repeats (tttta)n in the promoter of CYP11A1 and their relationships to polycystic ovary syndrome (PCOS) risk: a meta-analysis.

Molecular biology reports - 1 Jul 2014

Yu Min, Feng Ruizhi, Sun Xiaoxi, Wang Haojue, Wang Huan, Sang Qing, Jin Li, He Lin, Wang Lei

Abstract excerpt

Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases with an uncertain pathology and the most frequent incretory disorder in women of reproductive age, often leading to female infertility. Evidence has shown that genetic factors may contribute to the etiology of PCOS. Contradictory results have been reported concerning the association between PCOS and the CYP11A1 gene promoter -528 bp...

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PMID: 24610422
DOI: 10.1007/s11033-014-3314-3

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