Article
CYP19 gene variants affect the assisted reproduction outcome of women with polycystic ovary syndrome.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 May 2013
Lazaros Leandros, Xita Nectaria, Hatzi Elissavet, Takenaka Atsushi, Kaponis Apostolos, Makrydimas Georgios, Sofikitis Nikolaos, Stefos Theodoros, Zikopoulos Konstantinos, Georgiou Ioannis
Abstract excerpt
OBJECTIVE: Cytochrome P450 aromatase catalyzes the irreversible transformation of androgens into estrogens. The association of CYP19(TTTA)n polymorphism with the hormonal profile and the assisted reproduction outcome of women with polycystic ovary syndrome (PCOS) was explored. METHODS: One hundred and thirty-two women with PCOS and 200 with male-factor infertility, as controls, participated in the current study....
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