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Article

Association of CYP19 gene SNPs (rs7176005 and rs6493497) with polycystic ovary syndrome susceptibility in Northern Chinese women.

BMC medical genomics - 10 Mar 2025

Hao Ya-Li, Liu Chun-Miao, Wang Na, Zhou Rong-Miao, Wei Ya-Nan, Bai Xiao-Shuang, Huang Xi

Abstract excerpt

PURPOSE: The objective of this study was to elucidate the relationship between two single nucleotide polymorphisms (SNPs) rs7176005 and rs6493497 in CYP19 gene and the risk of polycystic ovary syndrome (PCOS) in Northern Chinese women. METHODS: In this case-control study, a total of 340 women with PCOS and 340 matched healthy controls were recruited. Polymerase chain reaction ligase detection reaction (PCR-LDR)...

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Topics

Adult

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Female

Humans

Young Adult

Aromatase

Case-Control Studies

China

Gene Frequency

Genetic Association Studies

Genetic Predisposition to Disease

Genotype

Linkage Disequilibrium

Polycystic Ovary Syndrome

Polymorphism, Single Nucleotide

East Asian People

Source

Open in PubMed Open full text

Identifiers

PMID: 40065436
DOI: 10.1186/s12920-025-02115-6
PMCID: PMC11892123

Provenance

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