Article
CYP19 gene: a genetic modifier of polycystic ovary syndrome phenotype.
Fertility and sterility - 1 Jun 2010
Xita Nectaria, Lazaros Leandros, Georgiou Ioannis, Tsatsoulis Agathocles
Abstract excerpt
OBJECTIVE: To evaluate the possible contribution of the (TTTA)n polymorphism of aromatase gene (CYP19) to the hyperandrogenic phenotype of polycystic ovary syndrome (PCOS). DESIGN: Case-control study. SETTING: Endocrine outpatients' clinic of a tertiary university hospital. PATIENT(S): One hundred eighty women with PCOS and 160 healthy controls of reproductive age. INTERVENTION(S): Blood sampling for genotype...
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