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Article

Association of the genetic polymorphism of the CYP19 intron 4[TTTA]n repeat with familial prostate cancer risk in a Japanese population.

Anticancer research - 1 Jan 2000

Suzuki Kazuhiro, Nakazato Haruki, Matsui Hiroshi, Koike Hidekazu, Okugi Hironobu, Ohtake Nobuaki, Takei Tomoyuki, Nakata Seiji, Hasumi Masaru, Yamanaka Hidetoshi

Abstract excerpt

BACKGROUND: Estrogen is crucial for development of benign prostate hyperplasia and prostate cancer. Aromatase (CYP19) is a key enzyme for estrogen synthesis in males. The genetic polymorphism of the CYP19 intron 4 [TTTA]n tetranucleotide has been studied in relation to breast cancer susceptibility. MATERIALS AND METHODS: We examined the association of the tetranucleotide repeat polymorphism of the CYP19 gene with...

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PMID: 14981949

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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