Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ewing Sarcoma: influence of TP53 Arg72Pro and MDM2 T309G SNPs.

Molecular biology reports - 1 Aug 2013

Thurow Helena S, Hartwig Fernando P, Alho Clarice S, Silva Deborah S B S, Roesler Rafael, Abujamra Ana Lucia, de Farias Caroline Brunetto, Brunetto Algemir Lunardi, Horta Bernardo L, Dellagostin Odir A, Collares Tiago, Seixas Fabiana K

Abstract excerpt

The Ewing Sarcoma is an important tumor of bone and soft tissue. The SNPs Arg72Pro of TP53 and T309G of MDM2 have been associated with many cancer types and have been differently distributed among populations worldwide. Based on a case-control design, this study aimed to assess the role of these SNPs in 24 Ewing Sarcoma patients, compared to 91 control individuals. DNA samples were extracted from blood and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Brazil

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Logistic Models

Share to Polymorphism, Restriction Fragment Length

Share to Proto-Oncogene Proteins c-mdm2

Share to Sarcoma, Ewing

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 23661019
DOI: 10.1007/s11033-013-2593-4

Genes

MDM2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ewing Sarcoma: influence of TP53 Arg72Pro and MDM2 T309G SNPs.PMID 23661019Read ↗

The functional MDM2 T309G genetic variant but not P53 Arg72Pro polymorphism is associated with risk of sarcomas: a meta-analysis.Semantic proximity Read ↗

Impact of MDM2 gene polymorphism on sarcoma risk.Semantic proximity Read ↗

MDM2 SNP309, gene-gene interaction, and tumor susceptibility: an updated meta-analysis.Semantic proximity Read ↗

MDM2 SNP309 contributes to tumor susceptibility: a meta-analysis.Semantic proximity Read ↗

MDM2 promoter polymorphism SNP309 contributes to tumor susceptibility: evidence from 21 case-control studies.Semantic proximity Read ↗

Prognostic impact of the MDM2SNP309 allele in leukemia and lymphoma.Semantic proximity Read ↗

Individual and combined effects of MDM2 SNP309 and TP53 Arg72Pro on breast cancer risk: an updated meta-analysis.Semantic proximity Read ↗

Significant Association of the MDM2 T309G Polymorphism with Breast Cancer Risk in a Turkish PopulationSemantic proximity Read ↗

Ewing's sarcoma: analysis of single nucleotide polymorphism in the EWS gene.Semantic proximity Read ↗

Correlations between MDM2 gene SNP309 polymorphism and susceptibility to leukemia.Semantic proximity Read ↗

MDM2 SNP309 and p53 codon 72 genetic polymorphisms and risk of AML: an Egyptian study.Semantic proximity Read ↗

Correlation of TP53 and MDM2 genotypes with response to therapy in sarcoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.