Article
Ewing's sarcoma: analysis of single nucleotide polymorphism in the EWS gene.
Gene - 10 Nov 2012
Silva Deborah S B S, Sawitzki Fernanda R, De Toni Elisa C, Graebin Pietra, Picanco Juliane B, Abujamra Ana Lucia, de Farias Caroline B, Roesler Rafael, Brunetto Algemir L, Alho Clarice S
Abstract excerpt
We aimed to investigate single nucleotide polymorphisms (SNPs) in the EWS gene breaking region in order to analyze Ewing's sarcoma susceptibility. The SNPs were investigated in a healthy subject population and in Ewing's sarcoma patients from Southern Brazil. Genotyping was performed by TaqMan® assay for allelic discrimination using Real-Time PCR. The analysis of incidence of SNPs or different SNP-arrangements...
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