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Article

MDM2 SNP309 and p53 codon 72 genetic polymorphisms and risk of AML: an Egyptian study.

Annals of clinical and laboratory science - 1 Jan 2014

El-Danasouri Nabil Mohsen, Ragab Shadia Hassan, Rasheed Maha Ameen, Ali El Saadany Zainab, Abd El-Fattah Safa Nabil

Abstract excerpt

BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous disease with numerous genetic abnormalities corresponding to a variety of subtypes. p53 is involved in multiple cellular pathways including apoptosis, transcriptional control, and cell cycle regulation. A single nucleotide polymorphism (SNP) at codon 72 of the p53 gene is associated with the risk for development of various neoplasms. MDM2 SNP309 is a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25361931

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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