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Article

Prognostic impact of the MDM2SNP309 allele in leukemia and lymphoma.

Oncotarget - 1 Jul 2010

Post Sean M, Pant Vinod, Abbas Hussein, Quintás-Cardama Alfonso

Abstract excerpt

A T-to-G germline single nucleotide polymorphism in the promoter region of MDM2 (SNP309) has been reported to markedly accelerate tumor formation in humans suggesting that it may represent a powerful cancer predisposing allele. Since its first description in 2004, a large number of retrospective analyses involving a wide variety of human malignancies have been reported, showing conflicting results regarding the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

Share to Proto-Oncogene Proteins c-mdm2

Source

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Identifiers

PMID: 21301048
DOI: 10.18632/oncotarget.123
PMCID: PMC3157715

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Prognostic impact of the MDM2SNP309 allele in leukemia and lymphoma.PMID 21301048Read ↗

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Association between the MDM2 T309G polymorphism and leukemia risk: a meta-analysis.Semantic proximity Read ↗

MDM2 SNP309 is associated with poor outcome in B-cell chronic lymphocytic leukemia.Semantic proximity Read ↗

Comprehensive Meta-Analysis on the Impact of the MDM2 SNP 309 T>G Gene Variant in Leukemia Susceptibility.Semantic proximity Read ↗

The Relationship Between MDM2 T309G Polymorphism and Leukemia in the Chinese Population: Evidence from a Meta-Analysis.Semantic proximity Read ↗

MDM2 SNP309 contributes to tumor susceptibility: a meta-analysis.Semantic proximity Read ↗

MDM2 promoter polymorphism SNP309 contributes to tumor susceptibility: evidence from 21 case-control studies.Semantic proximity Read ↗

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