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Article

Multiple activating and repressive cis-promoter regions regulate TNFSF15 expression in human primary mononuclear cells.

Cytokine - 1 Jul 2013

Gonsky Rivkah, Deem Richard L, Targan Stephan R

Abstract excerpt

TL1A/TNFSF15 has been associated with IBD (inflammatory bowel disease) in GWAS (genome-wide association study) and plays a role mediating mucosal inflammation in IBD. Higher TL1A expression is associated with disease severity in both patients and mouse models. Although TL1A has been studied extensively for IBD-associated SNPs, the cis/trans-regulatory regions are poorly defined. Herein we identify response...

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Identifiers

PMID: 23642711
DOI: 10.1016/j.cyto.2013.04.004
PMCID: PMC3889718

Genes

TNFSF15
TAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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