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Article

Transcriptional regulation of the human TNFSF11 gene in T cells via a cell type-selective set of distal enhancers.

Journal of cellular biochemistry - 1 Feb 2015

Bishop Kathleen A, Wang Xiaohua, Coy Heidi M, Meyer Mark B, Gumperz Jenny E, Pike J Wesley

Abstract excerpt

In addition to osteoblast lineage cells, the TNF-like factor receptor activator of NF-κB ligand (RANKL) is expressed in both B and T cells and may play a role in bone resorption. Rankl gene (Tnfsf11) expression in mouse T cells is mediated through multiple distal elements marked by increased transcription factor occupancy, histone tail acetylation, and RNA polymerase II recruitment. Little is known, however, of...

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Source

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Identifiers

PMID: 25211367
DOI: 10.1002/jcb.24974
PMCID: PMC4303342

Genes

TNFSF11
FOS
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Transcriptional regulation of the human TNFSF11 gene in T cells via a cell type-selective set of distal enhancers.PMID 25211367Read ↗

Mouse Rankl Expression Is Regulated in T Cells by c-Fos through a Cluster of Distal Regulatory Enhancers Designated the T Cell Control RegionSemantic proximity Read ↗

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