Article
Evolving abundance and clonal pattern of human germinal center B cells during childhood.
Blood - 1 Jul 1990
Valles-Ayoub Y, Govan H L, Braun J
Abstract excerpt
Childhood is a critical period for the development of the memory B-lymphocyte repertoire necessary in protective humoral immunity. This study addressed the natural history of memory B cells based on the previous identification of germinal center and mantle zone cells as the probable precursor and mature memory cell populations, respectively. Using flow cytometric quantitation of these B-cell subpopulations in...
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