Article
Human tonsillar germinal center T cells are a diverse and widely disseminated population.
European journal of immunology - 1 Nov 1999
Golby S J, Dunn-Walters D K, Spencer J
Abstract excerpt
Germinal center (GC) T cells are a poorly investigated population with a unique helper-inducer memory phenotype. Murine GC T cells have been demonstrated to be oligoclonal and antigen specific. The aim of this study was to investigate the diversity of human tonsillar GC T cells. Immunohistochemistry with a panel of different TCRVbeta family antibodies and sequencing of TCRgamma gene rearrangements obtained from...
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