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Article

The prevalence and prognostic significance of KRAS mutation in bladder cancer, chronic myeloid leukemia and colorectal cancer.

Molecular biology reports - 1 Jun 2013

Ouerhani Slah, Bougatef Karim, Soltani Ismail, Elgaaied Amel Ben Ammar, Abbes Salem, Menif Samia

Abstract excerpt

Mutations in the KRAS gene have been shown to play a key role in the pathogenesis of a variety of human tumours. However the mutational spectrum of KRAS gene differs by organ site. In this study, we have analysed the mutational spectrum of KRAS exon 1 in bladder tumours, colorectal cancer (CRC) and chronic myeloid leukemia (CML). A total of 366 patients were included in the present study (234 bladder tumours, 48...

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Source

Identifiers

PMID: 23640097
DOI: 10.1007/s11033-013-2512-8

Genes

KRAS
ABL1
BCR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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