Article
The prevalence and prognostic significance of KRAS mutation in bladder cancer, chronic myeloid leukemia and colorectal cancer.
Molecular biology reports - 1 Jun 2013
Ouerhani Slah, Bougatef Karim, Soltani Ismail, Elgaaied Amel Ben Ammar, Abbes Salem, Menif Samia
Abstract excerpt
Mutations in the KRAS gene have been shown to play a key role in the pathogenesis of a variety of human tumours. However the mutational spectrum of KRAS gene differs by organ site. In this study, we have analysed the mutational spectrum of KRAS exon 1 in bladder tumours, colorectal cancer (CRC) a...
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