Article
[Correlation of KRAS gene mutations and clinicopathologic parameters in colorectal carcinoma].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Sept 2012
Wang Qiong, Zhong Mei, Lü Ya-li, Yuan Jing, Wei Li-xin
Abstract excerpt
OBJECTIVE: To investigate the relationship between KRAS gene mutations and clinicopathological parameters in patients with colorectal carcinoma (CRC). METHODS: PCR-based direct sequencing was used to detect the mutations of KRAS gene and to correlate between clinicopathological characteristics and the presence of various KRAS mutations in 244 cases of CRC. RESULTS: KRAS mutations were identified in 92 cases...
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